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in vivo Research Associate

Guide Therapeutics is solving the challenge of DNA and RNA delivery. Founded by experts in RNA delivery, Guide Therapeutics has assembled a team of specialists in manufacturing, target selection, drug development, and business development.


Guide Therapeutics is seeking a highly skilled and motivated in vivo Research Associate to join our team. Under direction, the primary responsibilities for this position will be performing routine procedures for in vivo animal studies up to and including colony management and monitoring, animal identification, dosing, imaging, collecting tissues, and euthanasia as related to lipid nanoparticle (LNP) mediated RNA delivery.


  • Skilled in basic handling, observation, identification, and restraint of mice
  • Monitor general health and wellness of animals as directed by veterinary staff
  • Maintain supplies and equipment
  • Prepare drug dose, dosing sheets, and maintain record keeping
  • Demonstrate competency in:
    • Administering intravenous, intraperitoneal, intramuscular, retro-orbital, subcutaneous, and nebulized treatments
    • Collection of blood samples
    • Anesthesia induction, monitoring, and recovery
    • Cardiac perfusion followed by tissue harvest
  • Perform euthanasia, as necessary
  • Use the LI-COR Pearl imager for imaging mice and tissues, and subsequent analysis
  • Analyze data and maintain records in an electronic lab notebook
  • Ability to work effectively within a broader cross-functional team
  • Coordinate with research groups to ensure timely execution of experiments
  • Design, implement, troubleshoot, and modify experiments to reach desired goals
  • Communicate research and development findings with internal partners
  • Prepare and run laboratory experiments including sample collection and preparation, and data collection using established protocols
  • Will require daily local travel from main site in Tucker, GA and vivarium (15 miles/20 mins)


  • B.S. in life sciences with 2 years of relevant experience, or equivalent combination of training and experience
  • Familiar with animal handling, restraint, and procedures outlined above
  • Ability to establish and maintain positive relationships with employees, vendors, and external agencies
  • Broad skill set that enables communication across multiple disciplines (biology, chemistry)
  • Ability to work successfully both independently and in a collaborative environment
  • Follow and write standard operating procedures
  • Documentation of results and data analysis, attention to detail
  • Ensure safety and product quality throughout the laboratory environment
  • Capable of repetitive tasks and performing other duties as assigned
  • Basic computer skills including MS Office Suite

To apply, please send your CV to

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